Retrace - Mikrophan++ - Mol (CDr)

(8) Comments

  1. Togal
    Mol Cancer Ther ; DOI PubMed; Weekes CD, Lamberts LE, Borad MJ, Voortman J, McWilliams RR, et al. Phase I study of DMOTA, an antibody-drug conjugate targeting mesothelin, in patients with unresectable pancreatic or platinum-resistant ovarian cancer. Mol Cancer Ther ; DOI PubMed; Author: Xiaorong Wu, Thomas Kilpatrick, Ian Chau.
  2. Digore
    Sep 25,  · Comparison of 4 related Fab antibodies in complex with GM-CSF allowed us to retrace the structural changes introduced during in vitro affinity maturation using diversified CDR-H2 or CDR-L3 libraries. The CDR-H2 loop of the matured variant MOR was extended by 2 residues and showed additional changes compared to the parental CDR-H2 sequence Cited by: 7.
  3. Mazujind
    In various experiment (Table 9 and 10), randomisation of an individual CDR loop has resulted in 2 fold improvement in affinity Hemminki et al., ;Nagy et al., ;Brocks et al.,
  4. Dilkis
    The CDR H3s of the UCA and CAPVRC lacked a CDR H3 disulphide bond, exhibited greater disorder and were positioned more proximal to the light chain ; the appearance of the disulphide bond.
  5. Shamuro
    Mol Cancer Ther ;B Almhanna K, Kalebic T, Cruz C, Faris JE, R yan DP, et al. Phase I study of the investigational anti-guanylyl cyclase antibody-drug.
  6. Goltigis
    Nov 20,  · The CDR is a probe made of silicon with a flared tip formed on a cantilever with a rectangular shape. Figure 2 shows the geometric model of the CDR Here, L c, W c, and T c denote the length, width, and thickness of the cantilever, respectively. L t is the distance from the free end of the tip to the cantilever-base. l p and d p are the effective length and the effective diameter of the.
  7. Dam
    Nov 01,  · Resolving the Complexity of Antigen Receptor Repertoires. B and T lymphocytes of the adaptive immune system have the ability to recognize foreign molecules via an immense array of antigen-binding receptors (B cell and T cell receptors, BCR/TCR).The diversity of lymphocyte repertoires (short: ‘immune repertoires’) is a result of genetic recombination and diversification mechanisms.
  8. Zur
    Jun 30,  · The next-generation sequencing (NGS) analysis of human antibody repertoires has revealed the B-cell receptor (BCR) landscape at unprecedented resolution [1][2][3]. Applications include, but are not limited to, therapeutic antibody discovery, the delineation of B-cell maturation pathways, identifying immune biomarkers for infectious disease and cancer, providing insights into vaccine.

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